there can be no proof of sedatives. That said, I'm sure I read that after the event it was SUSPECTED/WONDERED ABOUT WHETHER the twins had been sedated because they slept through the kidnap, the mother's hysteria, the people in the rooms after the alarm went up and only came awake as friends were carrying them out of the apartment/villa.

I don't think any child was tested for sedatives and certainly NOT Madeleine.