I find Sunday mornings a lil trialing due to the fact that it's the first school day of the week. Kiddo is always grumpier on a Sunday morn and that's kinda tiresome. But the rest of the day is pretty much same o'l same o'l.
However in the past, as a working woman,I'd find Mondays (ie the first working day of the week)pretty hard.. but maybe that's cos I just hated my workplaces!